Celebrating more than 30 years of probiotic innovation

Scientifically reviewed by

Lotta Johansson, Microbiologist at BioGaia

Our experts

Curiosity, perseverance, excellence

For over three decades, BioGaia has been on an incredible journey, dedicated to exploring the fascinating world of probiotics.

What began as a quest to understand the intricate world of bacteria has evolved into a legacy of scientific excellence and consumer trust.

Our story is one of curiosity, perseverance, and a relentless pursuit of excellence. Here’s a glimpse into how our 30+ years of research have shaped the products you know and trust today.

The beginning: A vision takes root

Thirty years ago, the founders and a small group of visionary scientists came together with a shared dream: to unlock the potential of beneficial bacteria. They believed that these tiny organisms held the key to enhancing our everyday lives.

And with this bold vision, BioGaia was born.

Pioneering research

In 1990, through meticulous studies and trials, a groundbreaking discovery was made.

BioGaia scientists discovered the unique qualities of L. reuteri, a powerful probiotic species. The amazing L. reuteri became the cornerstone of our product line.

Limosilactobacillus reuteri (formerly Lactobacillus reuteri)

For 35 years, we have been researching L. reuteri, unlocking its novel potential for health. A probiotic naturally found in the human body, this remarkable bacterium has been co-evolving with humans since the beginning of time.

Every BioGaia product features strains of L. reuteri, which are carefully selected for their unique properties. These strains work in harmony with the body, offering distinct benefits that make BioGaia products a trusted choice for probiotics of healthcare professionals and consumers alike.

Clinical trials and research

Our commitment to conducting rigorous clinical trials ensures that our products are backed by solid evidence and trusted worldwide.

BioGaia’s probiotic supplements are among the most extensively studied in the world. Over 250 clinical studies involving around 22,000 people have documented the efficacy and safety of BioGaia’s L. reuteri.

Extensive global scientific network

At BioGaia, we believe in the power of collaboration, and our clinical trials are often conducted in partnership with leading universities, hospitals, and independent research organizations worldwide.

Our network includes: the Swedish University of Agricultural Sciences in Uppsala, Karolinska Institute in Stockholm, Sahlgrenska University Hospital in Gothenburg, Texas Children’s Hospital in the USA, and the University Hospitals of Bari and Turin in Italy.

These collaborations have enabled us to stay at the forefront of probiotic research and innovation.

You can trust that every BioGaia product is backed by decades of research and a commitment to delivering the very best in evidence-based probiotics.

Global research, open for all: Why BioGaia publishes all results

As a world leader, we believe in transparency and maintaining the highest standards in scientific research. That's why we encourage researchers to design and report their studies in a way that allows them to be published in respected medical journals. Our commitment is to publish all studies, no matter the outcome.

Additionally, BioGaia ensures that every study is ethically approved and registered on public websites like ClinicalTrials.gov & PubMed.gov. This openness allows everyone to benefit from our research, reinforcing our dedication to science.

Proof you can trust: How we conduct our clinical studies

The majority of our research is ‘randomized, double-blind, placebo-controlled trials’ (RCT). This method is preferred because it minimizes bias and provides the most reliable evidence for evaluating the effects of probiotics.

By following these standards, we can accurately assess the efficacy, safety, and benefits of probiotic strains, ensuring that the results are credible and can guide effective use in real-world settings.

Here’s why this design is especially important for probiotic research:

Randomly assigning participants to either the probiotic group or placebo group ensures that any differences in outcomes are due to the probiotic itself and not other factors.

In a double-blind trial, neither the participants nor the researchers know who is receiving the probiotic or placebo. This prevents expectations from influencing the results, which is crucial since the perceived health benefits of probiotics can be subjective.

Using a placebo allows for a direct comparison of the probiotic's effects versus no treatment, helping to establish the real impact of the probiotic strain.

RCTs in probiotics often focus on specific, measurable outcomes like changes in gut microbiota, immune response, or other markers of digestive health, providing clear and quantifiable evidence.

How BioGaia’s innovation became a worldwide sensation

Over the years, our dedication to research has led to trailblazing discoveries.

In 2000, BioGaia developed the world’s first chewable probiotic tablet, a groundbreaking innovation that made probiotics easier and more enjoyable to consume.

The chewable tablet was designed to provide all the benefits of probiotics in a convenient format, eliminating the need for swallowing pills or mixing powders.

Perfect for adults and children, our chewable probiotic quickly became a worldwide bestseller for its ease of use and great taste, revolutionizing how probiotics are consumed around the world.

In 2004, BioGaia introduced the world’s first probiotic oil drops, another pioneering innovation in probiotic delivery. These drops were designed to offer a convenient and effective way to incorporate probiotics into daily routines, especially for newborns and infants needing probiotic support. Since its launch, over 100 million baby drop products have been sold.

Scientific milestones

BioGaia is founded by Peter Rothschild and Jan Annwall, starting its journey in probiotic research and innovation.

BioGaia launches the world’s first chewable probiotic tablet, making probiotics more convenient and accessible for everyone.

A game-changing innovation, BioGaia introduces the first-ever probiotic oil drops, particularly beneficial for infants and children.

A world leader within oral health probiotics, BioGaia launches the first probiotic Lactobacilli for Oral Health.

BioGaia establishes the Foundation to Prevent Antibiotic Resistance, supporting global efforts to combat antibiotic resistance through research and education.

BioGaia opens a cutting-edge research laboratory focused on further advancing the science of beneficial bacteria.

BioGaia opens a sustainable-certified research laboratory focused on next-generation probiotics, further advancing the science of beneficial bacteria.

BioGaia’s probiotic supplements are among the most extensively studied worldwide.

International Scientific Association for Probiotics and Prebiotics (ISAPP)

BioGaia is proud to be a member of the International Scientific Association for Probiotics and Prebiotics (ISAPP), a global non-profit organization dedicated to advancing the science of probiotics, prebiotics, and related topics. Since its founding in 2002, ISAPP has brought together leading scientific experts worldwide to help shape the way probiotics and prebiotics are studied and understood.

ISAPP is committed to ensuring that research in this field is conducted with the highest scientific integrity and transparency standards. By promoting rigorous scientific methods and clear, science-based communication, the organization helps ensure that advancements in probiotics are grounded in reliable, trustworthy research.

At BioGaia, we share ISAPP’s dedication to upholding these principles and are proud to be part of an organization that is shaping the future of probiotics for the benefit of all.

Foundation to Prevent Antibiotic Resistance (PAR)

In 2017, BioGaia established the Foundation to Prevent Antibiotic Resistance, also known as the PAR Foundation, to tackle one of the most pressing global health threats: antibiotic resistance. This independent foundation is dedicated to supporting research, education, and information initiatives aimed at preventing the rise of antibiotic-resistant infections.

Antibiotic resistance poses a significant risk to public health, potentially undermining modern medicine. The overuse and misuse of antibiotics in healthcare, agriculture, and food production can turn common infections into severe, life-threatening conditions that are harder to treat. According to the World Health Organization (WHO), this growing issue demands urgent global action to preserve antibiotic effectiveness.

To address this challenge, BioGaia established the PAR Foundation, where our funding supports innovative research projects exploring new ways to combat antibiotic resistance and funds educational and awareness programs in Ecuador, Malaysia, and several African countries.

These efforts aim to enhance public understanding and implement effective measures to prevent resistance, ensuring that antibiotics remain a powerful tool for future generations.

The role of probiotics in antibiotic resistance

We believe probiotics play a crucial role in combating antibiotic resistance by supporting a healthy gut microbiota, which can be disrupted by antibiotic use. They help replenish beneficial bacteria lost during treatment, reducing the chances of harmful, resistant bacteria taking over.

Exploring new horizons: The probiotic advancements set to reshape well-being

As science advances and technology accelerates, the future of probiotics is filled with exciting possibilities for health and well-being.* The evolving landscape of probiotics promises innovative solutions that harness the power of beneficial bacteria in new and impactful ways.*

The next-gen probiotics revolution

Next-generation probiotics (NGPs) are at the forefront of this revolution. Leveraging cutting-edge technology, our researchers are now exploring advanced strains and formulations that were previously uncultivable. These new probiotics are designed for precision, offering targeted solutions.*

Although research on NGPs is still in its early stages, the potential is vast and promising. From our Centre of Excellence laboratory in Eslöv, Sweden, we are leading the way in metagenomics and strain development. Our work is pushing the boundaries of what’s possible with next-generation and traditional probiotics, paving the way for innovative approaches to support and enhance human health.*

Our dedication to advancing probiotic science remains unwavering as we look to the future. We continue to invest heavily in research, explore new possibilities, and develop innovative products that meet the evolving needs of our consumers.

Our goal is to continue providing you with high-quality probiotics that are backed by decades of scientific expertise.

The BioGaia story

BioGaia is a Swedish healthcare company that has been at the forefront of microbiome and probiotic research for more than 30 years.

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BioGaia’s Scientific Center of Excellence

At BioGaia, we are dedicated to pioneering the future of probiotics through cutting-edge research and innovation.

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Meet Lactobacillus reuteri 

BioGaia’s probiotic supplements with L. reuteri are among the most extensively studied in the world.

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